3-氨基-噻吩并[3,2-b]吡啶-2-羧酸甲酯合成路线 (共 3 条)
反应条件
sodium ethanolate in N,N-dimethyl-formamide 2 h;
参考文献
Miknis, Greg; Lyssikatos, Joseph P.; Laird, Ellen; Tarlton, Eugene; Buckmelter, Alexandre J.; Ren, Li; Rast, Bryson; Schlacter, Stephen T.; Wenglowsky, Steven Mark
Patent: US2007/49603 A1, 2007 ;
Location in patent: Page/Page column 38; 27 ;
US 20070049603 A1
反应条件
sodium methylate 1.) DMF, room temp., 20 min, 2.) room temp., 1.5 h; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 46, # 21 p. 4179 - 4182
反应条件
potassium tert-butylate 1.) irradiation, 75 min, liquid NH3; Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 39, # 24 p. 4153 - 4162