4-[[5-(氨基磺酰基)-1,3,4-噻二唑]氨基]-4-氧丁酸合成路线 （共 3 条）
反应条件
sodium hydroxide
T=60°C; 0.5 h;
参考文献
Antonaroli; Bianco; Brufani; Cellai; Lo Baido; Potier; Bonomi; Perfetti; Fiaschi; Segre
Journal of Medicinal Chemistry, 1992 , vol. 35, # 14 p. 2697 - 2703
参考文献
Pierce, William M.; Waite, Leonard C.; Taylor, K. Grant
Patent: US2005/143366 A1, 2005 ;
Location in patent: Page/Page column 18 ;
反应条件
1: NH3 / -78 °C
2: 70 percent / aq. NaOH / 0.5 h / 60 °C
View Scheme
参考文献
Antonaroli; Bianco; Brufani; Cellai; Lo Baido; Potier; Bonomi; Perfetti; Fiaschi; Segre
Journal of Medicinal Chemistry, 1992 , vol. 35, # 14 p. 2697 - 2703
