1: 1.) NaH / 1.) a) petroleum ether, THF, RT, 30 min, b) 60 deg C, 1 h, 2.) reflux, 36 h 2: 90 percent / HCl gas / CHCl3; methanol / 0.75 h / Ambient temperature 3: triethylamine / benzene / 2 h / Ambient temperature 4: 0.115 g / acetonitrile / 24 h / 65 °C View Scheme

1: triethylamine / benzene / 2 h / Ambient temperature 2: 0.115 g / acetonitrile / 24 h / 65 °C View Scheme

1: 1.) NaH / 1.) a) petroleum ether, THF, RT, 30 min, b) 60 deg C, 1 h, 2.) reflux, 36 h 2: 90 percent / HCl gas / CHCl3; methanol / 0.75 h / Ambient temperature 3: triethylamine / benzene / 2 h / Ambient temperature 4: 0.115 g / acetonitrile / 24 h / 65 °C View Scheme

1: 75 percent / LiAlH4 / diethyl ether / 1.) 0 deg C, 30 min, 2.) RT, 2 h 2: 1.) NaH / 1.) a) petroleum ether, THF, RT, 30 min, b) 60 deg C, 1 h, 2.) reflux, 36 h 3: 90 percent / HCl gas / CHCl3; methanol / 0.75 h / Ambient temperature 4: triethylamine / benzene / 2 h / Ambient temperature 5: 0.115 g / acetonitrile / 24 h / 65 °C View Scheme

1: 90 percent / HCl gas / CHCl3; methanol / 0.75 h / Ambient temperature 2: triethylamine / benzene / 2 h / Ambient temperature 3: 0.115 g / acetonitrile / 24 h / 65 °C View Scheme

in acetonitrile T=65°C; 24 h;