反应条件
1: (6R,7R)-7-amino-3-[(Z)-1-propen-1-yl]-3-cephem-4-carboxylic acid With 1H-imidazole; chloro-trimethyl-silane in dichloromethane 3 - 4 h; Heating / reflux; 2: C16H19NO7 in DMF (N,N-dimethyl-formamide); dichloromethane T=-45 - -20°C; 2.5 h; 3: With hydrogenchloride in DMF (N,N-dimethyl-formamide); dichloromethane; water T=0 - 5°C; 0.25 h;