1-乙炔基-2-(甲硫基)苯合成路线 （共 7 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran
T=20°C; 0.5 h;
参考文献
Chen, Chin-Chau; Chen, Chu-Mei; Wu, Ming-Jung
Journal of Organic Chemistry, 2014 , vol. 79, # 10 p. 4704 - 4711
反应条件
n-butyllithium; potassium tert-butylate in tetrahydrofuran; hexane
T=-60 - -50°C;
参考文献
Hommes, Hendrik; Verkruijsse, Hermann D.; Brandsma, Lambert
Journal of the Chemical Society, Chemical Communications, 1981 , # 8 p. 366 - 367
反应条件
ammonia; sodium amide in diethyl ether
T=-35°C;
参考文献
Schroth, Werner; Jordan, Hartwig; Spitzner, Roland
Tetrahedron Letters, 1995 , vol. 36, # 9 p. 1421 - 1424
反应条件
sodium hydride in benzene
1 h; Heating;
参考文献
Chowdhury, Morshed Alam; Dong, Ying; Chen, Qiao-Hong; Abdellatif, Khaled R.A.; Knaus, Edward E.
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 4 p. 1948 - 1956
反应条件
T=750°C; P=0.1 - 1 Torr;
参考文献
Aitken, R. Alan; Horsburg, Caroline E. R.; McCreadie, J. Graeme; Seth, Shirley
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 13 p. 1727 - 1732
反应条件
1: tetrakis(triphenylphosphine) palladium(0); copper(l) iodide; N-butylamine / diethyl ether / 6 h / 20 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C
View Scheme
参考文献
Lin, Cheng-Han; Chen, Chin-Chau; Wu, Ming-Jung
Chemistry - A European Journal, 2013 , vol. 19, # 8 p. 2578 - 2581
反应条件
1: 69 percent / Et3N / toluene / 3 h / Ambient temperature
2: 38 percent / 750 °C / 0.1 - 1 Torr
View Scheme
参考文献
Aitken, R. Alan; Horsburg, Caroline E. R.; McCreadie, J. Graeme; Seth, Shirley
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 13 p. 1727 - 1732
