(2E,4E)-1-吡咯烷-1-基癸-2,4-二烯-1-酮合成路线 （共 29 条）
反应条件
tetrabutyl-ammonium chloride; palladium diacetate; potassium carbonate in N,N-dimethyl-formamide
T=70°C; Mizoroki-Heck reaction; 5 h; Inert atmosphere;
参考文献
Shakhmaev; Ishbaeva; Sunagatullina; Zorin
Russian Journal of General Chemistry, 2011 , vol. 81, # 9 p. 1915 - 1917
反应条件
potassium carbonate in acetonitrile
T=25°C; 7 h;
参考文献
Huang, Y. Z.; Shi, Lilan; Yang, Jianhua; Zhang, Jingtao
Tetrahedron Letters, 1987 , vol. 28, # 19 p. 2159 - 2162
反应条件
aluminum oxide; potassium hydroxide; dibromo-difluoro-methane in dichloromethane
T=20°C; 1 h;
参考文献
Li, Yang; Zhang, Yu; Huang, Zhi; Cao, Xiaoping; Gao, Kun
Canadian Journal of Chemistry, 2004 , vol. 82, # 5 p. 622 - 630
反应条件
Cl2Ni(1,2-bis(diphenylphosphino)ethane) in tetrahydrofuran
5 h; Ambient temperature;
参考文献
Babudri, Francesco; Fiandanese, Vito; Naso, Francesco; Punzi, Angela
Tetrahedron Letters, 1994 , vol. 35, # 13 p. 2067 - 2070
反应条件
Sn[N(SiMe3)2]2 in hexane
12 h; Ambient temperature;
参考文献
Strunz, George M.; Finlay, Heather J.
Canadian Journal of Chemistry, 1996 , vol. 74, # 3 p. 419 - 432
反应条件
in tetrahydrofuran
T=-40°C; 2 h;
参考文献
Carmen Bernabeu
Tetrahedron Letters, 1995 , vol. 36, # 22 p. 3901 - 3904
反应条件
triethylamine; trichlorophosphate in dichloromethane
1) 0 deg C, 2 h, 2) room temperature, 1 h;
参考文献
Bari; Sattar; Vig; Kumar; Vasisht
Journal of the Indian Chemical Society, 1990 , vol. 67, # 12 p. 995 - 996
反应条件
1: 1) Li, 2) Fe(NO3)3 / liquid ammonia
2: 84 percent / H2 / Lindlar's catalyst / hexane
3: 66 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / low temperature
4: 1) NaH / 1) THF, oil, 2a) room temperature, 3 h, b) 50 deg C, 3 h
5: 70 percent / KOH / methanol / 10 h / Ambient temperature
6: 56 percent / triethylamine, POCl3 / CH2Cl2 / 1) 0 deg C, 2 h, 2) room temperature, 1 h
View Scheme
参考文献
Bari; Sattar; Vig; Kumar; Vasisht
Journal of the Indian Chemical Society, 1990 , vol. 67, # 12 p. 995 - 996
反应条件
1: 84 percent / H2 / Lindlar's catalyst / hexane
2: 66 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / low temperature
3: 1) NaH / 1) THF, oil, 2a) room temperature, 3 h, b) 50 deg C, 3 h
4: 70 percent / KOH / methanol / 10 h / Ambient temperature
5: 56 percent / triethylamine, POCl3 / CH2Cl2 / 1) 0 deg C, 2 h, 2) room temperature, 1 h
View Scheme
参考文献
Bari; Sattar; Vig; Kumar; Vasisht
Journal of the Indian Chemical Society, 1990 , vol. 67, # 12 p. 995 - 996
反应条件
1: 63 percent / Ag(CF3COO), 4 Angstroem mol. sieves / tetrahydrofuran / 7 h / Ambient temperature
2: 68 percent / 3 molpercent NiCl2(dppe) / tetrahydrofuran / 5 h / Ambient temperature
View Scheme
参考文献
Babudri, Francesco; Fiandanese, Vito; Naso, Francesco; Punzi, Angela
Tetrahedron Letters, 1994 , vol. 35, # 13 p. 2067 - 2070
