1: 73 percent / CH2Cl2 / 8 h / Ambient temperature 2: 94.5 percent / Cu(OAc)2*H2O, HCl(g)/air / CH2Cl2 3: 69 percent / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 0.5 h / -3 °C 4: 63 percent / LiOH*H2O / tetrahydrofuran; H2O / 20.5 h / Ambient temperature; purification with conc. H2SO4 View Scheme

triethylamine in diethyl ether T=25°C; 20 h; Yield given;

1: Br2 / CH2Cl2 / Heating 2: Et3N / diethyl ether / 20 h / 25 °C View Scheme

1: CH2Cl2 / 7 h / 25 °C 2: dry hydrogen chloride / CH2Cl2 / 10 h 3: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C 4: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating 5: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C 6: NH4OH / H2O / 30 h / 23 °C View Scheme

1: CH2Cl2 2: 21 percent / BBr3 / CH2Cl2 3: 93 percent / tBuN(O)COPh / CH2Cl2; methanol View Scheme

1: 73 percent / CH2Cl2 / 8 h / Ambient temperature 2: 94.5 percent / Cu(OAc)2*H2O, HCl(g)/air / CH2Cl2 3: 69 percent / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 0.5 h / -3 °C View Scheme