1: chloroacetic acid With dicyclohexyl-carbodiimide in dichloromethane T=20°C; 0.5 h; 2: dibutylamine With 4-(N,N-dimethlyamino)pyridine in dichloromethane T=20°C;
参考文献
Falco, Jose Luis; Pique, Maria; Gonzalez, Miguel; Buira, Irma; Mendez, Eva; Terencio, Jose; Perez, Cristina; Princep, Marta; Palomer, Albert; Guglietta, Antonio
European Journal of Medicinal Chemistry, 2006 , vol. 41, # 8 p. 985 - 990
1: carbon disulfide; 4-chloro-benzylamine With sodium hydroxide in ethanol T=100°C; Microwave irradiation; 2: chloroacetic acid in ethanol T=100°C; 0.0833333 h; Microwave irradiation; 3: With hydrogenchloride in ethanol; water T=120°C; 0.5 h; Microwave irradiation;
参考文献
Nitsche, Christoph; Schreier, Verena N.; Behnam, Mira A. M.; Kumar, Anil; Bartenschlager, Ralf; Klein, Christian D.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 21 p. 8389 - 8403
