1: chloroacetic acid With lithium diisopropyl amide in tetrahydrofuran T=-78°C; Metallation; 0.5 h; 2: benzaldehyde With 4,4'-di-tert-butylbiphenyl; lithium in tetrahydrofuran T=-78°C; Addition; 1 h; 3: With water in tetrahydrofuran T=-78 - 20°C; Hydrolysis;
参考文献
Pastor, Isidro M.; Yus, Miguel
Tetrahedron Letters, 2000 , vol. 41, # 28 p. 5335 - 5339