1: 1.)POCl3 / 1.) CH2Cl2, 0 deg C, 0.5 h, 2.) CH2Cl2, RT, 3 h 2: 86 percent / NaBH4, 5percent aq. NaOH / methanol / 6 h / Ambient temperature 3: 1.) 3-chloroperbenzoic acid, 2.) 10-camphorsulfonic acid / 1.) benzene, RT, 2 h, 2.) benzene, RT, 15 min 4: 97 percent / H2, Na2HPOP4 / 5percent Pd/C / methanol / 2 h 5: 85 percent / zinc triflate / CH2Cl2 / 16 h / Heating 6: 78 percent / H2 / W-2 Raney Ni / ethanol / 36 h / Heating View Scheme

1: POCl3 / CH2Cl2 / 4 h / Ambient temperature 2: 1.) n-BuLi, TMEDA / 1.) THF, hexane, -78 deg C to rt, 2.) THF, hexane, 0 deg C to rt 3: 90 percent / KHCO3 / methanol; H2O / 12 h / 40 °C 4: CuSO4*5H2O / toluene / 3 h / 70 °C View Scheme

trichlorophosphate 1.) CH2Cl2, 0 deg C, 0.5 h, 2.) CH2Cl2, RT, 3 h; Yield given. Multistep reaction;