(R)-6-氟-茚满-1-胺合成路线 (共 1 条)
反应条件
1.1: (R)-tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c]-[1,3,2]oxazaborole; dimethylsulfide borane complex / toluene / 3 h / -10 - -5 °C / |Inert atmosphere 1.2: 0.75 h / 10 °C 2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene; diphenyl phosphoryl azide / toluene / 10 - 20 °C 3.1: hydrogen; 5 palladium on charcoal / ethanol / 1 h / 2585.81 Torr / |Inert atmosphere View Scheme