反应条件
1: 94 percent / imidazole / dimethylformamide / 4 h / 25 °C
2: 1.) n-butyllithium, 2.) Gilman reagent, cuprrous cyanide, HMPA
3: H2, triethylamine / Lindlar catalyst / hexane / 760 Torr
4: tetra-n-butylammonium fluoride / tetrahydrofuran / 25 °C
5: 25 °C / saponification
View Scheme
参考文献
Corey, E.J.; Kang, Jahyo
Journal of the American Chemical Society, 1981 , vol. 103, # 15 p. 4618 - 4619