9-苄基-2,6-二氯-9h-嘌呤合成路线 （共 35 条）
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran
10 h; Ambient temperature;
参考文献
Toyota; Katagiri; Kaneko
Synthetic Communications, 1993 , vol. 23, # 9 p. 1295 - 1305
反应条件
in ethanol; water
18 h; Heating;
参考文献
Kelley; Linn; Selway
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1360 - 1363
反应条件
in ethanol; water
18 h; Heating;
参考文献
Kelley; Linn; Selway
Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1360 - 1363
反应条件
1: 72 percent / methanol / 18 h / Ambient temperature
2: 67 percent / H2, NaOAc / 5percent Pd/C / ethanol / 6.5 h / 1520 - 2280 Torr
View Scheme
参考文献
Kelley, James L.; Linn, James A.; Krochmal, Mark P.; Selway, J. W. T.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 10 p. 2001 - 2004
反应条件
ammonia in methanol
T=120°C; P=10500.8 Torr; 15 h; microwave irradiation;
参考文献
Weterings, Jimmy J.; Khan, Selina; van der Heden, Gerbrand J.; Drijfhout, Jan W.; Melief, Cornelis J.M.; Overkleeft, Herman S.; van der Burg, Sjoerd H.; Ossendorp, Ferry; van der Marel, Gijsbert A.; Filippov, Dmitri V.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 12 p. 3258 - 3261
