3-(哌啶-4-基)-3,4-二氢喹唑啉-2(1H)-酮合成路线 (共 5 条)
反应条件
hydrogen; Pd/C in ethanol T=60°C; P=1500.15 Torr;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2005/77931 A2, 2005 ;
Location in patent: Page/Page column 12-13 ;
WO 2005/077931 A2
反应条件
1: in acetonitrile Reflux; 2: With hydrogen; palladium(II) oxide hydrate in methanol
参考文献
WO2011/143444 A2, ;
Page/Page column 8; 87-90 ;
反应条件
1: sodium tetrahydroborate; methanol 2: hydrogen / palladium on activated charcoal / ethanol 3: acetonitrile / Reflux View Scheme
反应条件
1: sodium tetrahydroborate; methanol 2: hydrogen / palladium on activated charcoal / ethanol 3: acetonitrile / Reflux View Scheme
反应条件
1: hydrogen / palladium on activated charcoal / ethanol 2: acetonitrile / Reflux View Scheme