N-叔丁氧羰基-4-哌啶酮合成路线

参考文献

Hoffmann-La Roche Inc.; Firooznia, Fariborz; Lin, Tai-An; Mertz, Eric; Sidduri, Achyutharao; So, Sung-Sau; Tilley, Jefferson Wright
Patent: US2013/150407 A1, 2013 ;

79099-07-3N-叔丁氧羰基-4-哌啶酮+

105-58-8碳酸二乙酯

98977-34-51-Boc-4-氧-3-哌啶羧酸乙酯

参考文献

PFIZER INC.; NINKOVIC, Sacha; BRAGANZA, John Frederick; COLLINS, Michael Raymond; KATH, John Charles; LI, Hui; RICHTER, Daniel Tyler
Patent: WO2010/16005 A1, 2010 ;
Location in patent: Page/Page column 95-96 ;
WO 2010/016005 A1

79099-07-3N-叔丁氧羰基-4-哌啶酮+

4755-77-5草酰氯单乙酯

98977-34-51-Boc-4-氧-3-哌啶羧酸乙酯

参考文献

Piotrowski, David W.; Futatsugi, Kentaro; Warmus, Joseph S.; Orr, Suvi T. M.; Freeman-Cook, Kevin D.; Londregan, Allyn T.; Wei, Liuqing; Jennings, Sandra M.; Herr, Michael; Coffey, Steven B.; Jiao, Wenhua; Storer, Gregory; Hepworth, David; Wang, Jian; Lavergne, Sophie Y.; Chin, Janice E.; Hadcock, John R.; Brenner, Martin B.; Wolford, Angela C.; Janssen, Ann M.; Roush, Nicole S.; Buxton, Joanne; Hinchey, Terri; Kalgutkar, Amit S.; Sharma, Raman; Flynn, Declan A.
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 1 p. 63 - 68

7646-93-7硫酸氢钾+

79099-07-3N-叔丁氧羰基-4-哌啶酮+

105-58-8碳酸二乙酯

98977-34-51-Boc-4-氧-3-哌啶羧酸乙酯

参考文献

Taisho Pharmaceutical Co., Ltd.
Patent: US6600038 B1, 2003 ;

79099-07-3N-叔丁氧羰基-4-哌啶酮

183673-66-71-(N-BOC)-4-(N-FMOC-氨基)-4-哌啶甲酸

参考文献

Wysong, Christopher L.; Yokum, T. Scott; Morales, Guillermo A.; Gundry, Rebekah L.; McLaughlin, Mark L.; Hammer, Robert P.
Journal of Organic Chemistry, 1996 , vol. 61, # 22 p. 7650 - 7651

79099-07-3N-叔丁氧羰基-4-哌啶酮

87120-72-71-Boc-4-氨基哌啶

参考文献

SmithKline Beecham Corporation
Patent: US6335340 B1, 2002 ;
Location in patent: Example 23 ;

87120-72-71-Boc-4-氨基哌啶

参考文献

SmithKline Beecham Corporation
Patent: US6214844 B1, 2001 ;

87120-72-71-Boc-4-氨基哌啶

参考文献

SmithKline Beecham Corporation
Patent: US6046208 A1, 2000 ;

79099-07-3N-叔丁氧羰基-4-哌啶酮

183673-71-4N-BOC-4-氨基-4-羧酸哌啶

参考文献

Wysong, Christopher L.; Yokum, T. Scott; Morales, Guillermo A.; Gundry, Rebekah L.; McLaughlin, Mark L.; Hammer, Robert P.
Journal of Organic Chemistry, 1996 , vol. 61, # 22 p. 7650 - 7651

79099-07-3N-叔丁氧羰基-4-哌啶酮

84163-16-65-氟-3-(4-哌啶基)-1,2-苯并异噁唑盐酸盐

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 24 p. 6773 - 6776