N-叔丁氧羰基-4-哌啶酮合成路线

参考文献

Gruenenthal GmbH
Patent: US2009/264400 A1, 2009 ;
Location in patent: Page/Page column 97 ;
US 20090264400 A1

634616-95-81,3-二氢-1-[1'-[(2-甲基苯基)甲基][1,4'-联哌啶]-4-基]-2H-苯并咪唑-2-酮

参考文献

Rasheed, Mohammed Abdul; Shaik, Nagul Meera; Nirogi, Ramakrishna
Synthetic Communications, 2013 , vol. 43, # 13 p. 1796 - 1801

79099-07-3N-叔丁氧羰基-4-哌啶酮

644982-19-44-(1-氰基-2-乙氧基-2-氧代乙基)-4-苯基哌啶-1-羧酸叔丁酯

参考文献

Kazmierski, Wieslaw M.; Anderson, Don L.; Aquino, Christopher; Chauder, Brian A.; Duan, Maosheng; Ferris, Robert; Kenakin, Terrence; Koble, Cecilia S.; Lang, Dan G.; Mcintyre, Maggie S; Peckham, Jennifer; Watson, Christian; Wheelan, Pat; Spaltenstein, Andrew; Wire, Mary B.; Svolto, Angilique; Youngman, Michael
Journal of Medicinal Chemistry, 2011 , vol. 54, # 11 p. 3756 - 3767

79099-07-3N-叔丁氧羰基-4-哌啶酮+

参考文献

Hansen, Peter; Pettersson, Lars
Patent: US2003/144267 A1, 2003 ;

79099-07-3N-叔丁氧羰基-4-哌啶酮

54477-05-34-(2-苯并呋喃)-哌啶

参考文献

Ye, Xiang-Yang; Morales, Christian L.; Wang, Ying; Rossi, Karen A.; Malmstrom, Sarah E.; Abousleiman, Mojgan; Sereda, Larisa; Apedo, Atsu; Robl, Jeffrey A.; Miller, Keith J.; Krupinski, John; Wacker, Dean A.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 11 p. 2539 - 2545

496-15-1吲哚啉+

79099-07-3N-叔丁氧羰基-4-哌啶酮

400828-91-34-吲哚啉-1-哌啶-1-羧酸叔丁酯

参考文献

GLAXO GROUP LIMITED
Patent: WO2009/16227 A2, 2009 ;
Location in patent: Page/Page column 13-14 ;
WO 2009/016227 A2

59-48-32-吲哚酮+

79099-07-3N-叔丁氧羰基-4-哌啶酮

400797-94-64-(2-氧代吲哚啉-1-基)哌啶-1-羧酸叔丁酯

参考文献

Yang, Shyh-Ming; Tang, Yuting; Zhang, Rui; Lu, Huajun; Kuo, Gee-Hong; Gaul, Michael D.; Li, Yaxin; Ho, George; Conway, James G.; Liang, Yin; Lenhard, James M.; Demarest, Keith T.; Murray, William V.
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 24 p. 6773 - 6776

35613-44-6(2-氨基-苯基)-乙酸甲酯+

79099-07-3N-叔丁氧羰基-4-哌啶酮

400797-94-64-(2-氧代吲哚啉-1-基)哌啶-1-羧酸叔丁酯

参考文献

Butler, Christopher R.; Cai, Hui; Edwards, James P.; Grice, Cheryl A.; Gu, Yin; Gustin, Darin J.; Karlsson, Lars; Khatuya, Haripada; Meduna, Steven P.; Pio, Barbara A.; Sehon, Clark A.; Sun, Siquan; Tays, Kevin L.; Thurmond, Robin L.; Wei, Jianmei
Patent: US2005/101587 A9, 2005 ;

79099-07-3N-叔丁氧羰基-4-哌啶酮

400797-94-64-(2-氧代吲哚啉-1-基)哌啶-1-羧酸叔丁酯

参考文献

Sumiyoshi, Takaaki; Enomoto, Takeshi; Takai, Kentaro; Takahashi, Yoko; Konishi, Yasuko; Uruno, Yoshiharu; Tojo, Kengo; Suwa, Atsushi; Matsuda, Harumi; Nakako, Tomokazu; Sakai, Mutsuko; Kitamura, Atsushi; Uematsu, Yasuaki; Kiyoshi, Akihiko
ACS Medicinal Chemistry Letters, 2013 , vol. 4, # 2 p. 244 - 248

79099-07-3N-叔丁氧羰基-4-哌啶酮+

105-36-2溴乙酸乙酯

401811-97-04-[(乙氧基羰基)甲基]-4-羟基哌啶-1-羧酸叔丁酯

参考文献

ZALICUS PHARMACEUTICALS LTD .; PAJOUHESH , Hassan; ZHU, Yongbao; ZHOU, Yuanxi; GRIMWOOD, Mike; SIMONSON, Eric
Patent: WO2011/32291 A1, 2011 ;
Location in patent: Page/Page column 51-52 ;
WO 2011/032291 A1