2-(甲基磺酰基)-5-硝基吡啶合成路线 （共 8 条）
参考文献
Forrest; Walker
Journal of the Chemical Society, 1948 , p. 1939,1942
参考文献
Forrest; Walker
Journal of the Chemical Society, 1948 , p. 1939,1942
反应条件
iron; ammonium chloride in methanol; water 1 h; Reflux;
参考文献
ELI LILLY AND COMPANY; BLEISCH, Thomas, John; COATES, David, Andrew; HUGHES, Norman, Earle; JONES, Scott, Alan; NORMAN, Bryan, Hurst
Patent: WO2013/66640 A1, 2013 ;
Location in patent: Page/Page column 19 ;
反应条件
acetic acid in water; ethyl acetate
参考文献
Pfizer Inc.
Patent: US6531492 B1, 2003 ;
反应条件
sodium periodate; ruthenium trichloride in water; acetonitrile
T=20°C; 16 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2009/149139 A1, 2009 ;
Location in patent: Page/Page column 58 ;
反应条件
sulfuric acid in methanol; ethanol; water; acetone
参考文献
Cheng, Hengmiao; Sakya, Subas Man; Dutra, Jason Kenneth
Patent: US2002/58681 A1, 2002 ;
反应条件
in dimethyl sulfoxide
参考文献
Pfizer Inc.
Patent: US6531492 B1, 2003 ;
反应条件
1: Na2S*9H2O / dimethylformamide / 1 h / 20 °C
2: dimethylformamide / 24 h / 20 °C
3: potassium permanganate / acetic acid; H2O / 0.33 h / 25 °C
View Scheme
参考文献
Bourdais; Dauvillier; Gayral; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 3 p. 233 - 239
