3-甲基-1,8-萘啶-2,4-二醇合成路线 (共 2 条)
反应条件
1: With sodium t-butanolate in tetrahydrofuran
T=20 - 100°C; 4.68333 h;
2: With hydrogenchloride in water
pH=7;
参考文献
AMGEN INC.; BROWN, Matthew; CHEN, Yi; CUSHING, Timothy D.; GONZALEZ LOPEZ DE TURISO, Felix; HE, Xiao; KOHN, Todd J.; LOHMAN, Julia Winslow; PATTAROPONG, Vatee; SEGANISH, Jennifer; SHIN, Youngsook; SIMARD, Jillian L.
Patent: WO2010/151737 A2, 2010 ;
Location in patent: Page/Page column 207-208 ;
WO 2010/151737 A2
反应条件
Microwave irradiation;
参考文献
Maringanti, Thirumala Chary; Eppakayala, Laxminarayana; Sripelly, Shiva Shankar; Atmakuri, Narender
Heterocyclic Communications, 2009 , vol. 15, # 1 p. 35 - 41