乙基(2S,4R)-4-甲基哌可酸酯合成路线 （共 3 条）
反应条件
hydrogen; palladium hydroxide - carbon in ethanol
P=760 Torr; Ambient temperature;
参考文献
Bailey, Patrick D.; Brown, George R.; Korber, Fritjof; Reed, Amanda; Wilson, Robert D.
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1263 - 1282
反应条件
1: H2 / 3percent Pt/C / ethyl acetate / 16 h / 760 Torr
2: 72 percent / H2 / 10percent Pd(OH)2/C / ethanol / 8 h / 760 Torr
View Scheme
参考文献
Bailey, Patrick D.; Brown, George R.; Korber, Fritjof; Reed, Amanda; Wilson, Robert D.
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1263 - 1282
反应条件
1: TFA, H2O / dimethylformamide / 30 h / Ambient temperature
2: H2 / 3percent Pt-C / ethyl acetate / 16 h / 760 Torr / Ambient temperature
3: 72 percent / H2 / Pd(OH)2-C / ethanol / 760 Torr / Ambient temperature
View Scheme
参考文献
Bailey, Patrick D.; Wilson, Robert D.; Brown, George R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 5 p. 1337 - 1340
