1: 97 percent / dimethyl sulfate, potassium carbonate / acetone 2: 80 percent / 2 percent methanolic sodium hydroxide / methanol / 0.2 h / Heating 3: 95 mg / anhyd. pyridine, O3 / CH2Cl2 / -78 °C 4: 84 percent / conc. sulfuric acid / 2 h / 200 °C View Scheme

1: 97 percent / dimethyl sulfate, potassium carbonate / acetone 2: 80 percent / 2 percent methanolic sodium hydroxide / methanol / 0.2 h / Heating 3: 95 mg / anhyd. pyridine, O3 / CH2Cl2 / -78 °C View Scheme