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乙二醇
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63148-62-9
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二甲基亚砜
碳酸氢钠
471-34-1
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乙二醇
甲醛
63148-62-9
MDI
丁酮
二甲基亚砜
碳酸氢钠
471-34-1
792122-30-6
合成路线
(共 6 条)
792122-64-6
+
74-89-5
甲胺
→
反应条件
792122-30-6
反应条件
in ethanol; water T=100°C; 3 h;
参考文献
Beadle, Christopher D.; Boot, John; Camp, Nicholas P.; Dezutter, Nancy; Findlay, Jeremy; Hayhurst, Lorna; Masters, John J.; Penariol, Roberta; Walter, Magnus W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4432 - 4437
868701-20-6
+
74-89-5
甲胺
→
反应条件
792122-30-6
反应条件
in ethanol; water T=60°C; 2 h;
参考文献
Beadle, Christopher D.; Boot, John; Camp, Nicholas P.; Dezutter, Nancy; Findlay, Jeremy; Hayhurst, Lorna; Masters, John J.; Penariol, Roberta; Walter, Magnus W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4432 - 4437
108-86-1
溴代苯
→
反应条件
792122-30-6
反应条件
1.1: 80 percent / CuI; trans-cyclohexane-1,3-diamine; K2CO3 / dioxane / 125 °C 2.1: lithium hexamethyldisilazide / tetrahydrofuran / 0.5 h / -78 °C 2.2: tetrahydrofuran / -78 - 20 °C 3.1: ethanol; H2O / 3 h / 100 °C View Scheme
参考文献
Beadle, Christopher D.; Boot, John; Camp, Nicholas P.; Dezutter, Nancy; Findlay, Jeremy; Hayhurst, Lorna; Masters, John J.; Penariol, Roberta; Walter, Magnus W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4432 - 4437
553-03-7
3,4-二氢-2(1H)-喹啉酮
→
反应条件
792122-30-6
反应条件
1.1: 80 percent / CuI; trans-cyclohexane-1,3-diamine; K2CO3 / dioxane / 125 °C 2.1: lithium hexamethyldisilazide / tetrahydrofuran / 0.5 h / -78 °C 2.2: tetrahydrofuran / -78 - 20 °C 3.1: ethanol; H2O / 3 h / 100 °C View Scheme
参考文献
Beadle, Christopher D.; Boot, John; Camp, Nicholas P.; Dezutter, Nancy; Findlay, Jeremy; Hayhurst, Lorna; Masters, John J.; Penariol, Roberta; Walter, Magnus W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4432 - 4437
67176-93-6
→
反应条件
792122-30-6
反应条件
1.1: lithium hexamethyldisilazide / tetrahydrofuran / 0.5 h / -78 °C 1.2: tetrahydrofuran / -78 - 20 °C 2.1: ethanol; H2O / 3 h / 100 °C View Scheme
参考文献
Beadle, Christopher D.; Boot, John; Camp, Nicholas P.; Dezutter, Nancy; Findlay, Jeremy; Hayhurst, Lorna; Masters, John J.; Penariol, Roberta; Walter, Magnus W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4432 - 4437
868701-18-2
→
反应条件
792122-30-6
反应条件
1: 100 percent / Et3N / tetrahydrofuran / 3 h / 20 °C 2: 81 percent / ethanol; H2O / 2 h / 60 °C View Scheme
参考文献
Beadle, Christopher D.; Boot, John; Camp, Nicholas P.; Dezutter, Nancy; Findlay, Jeremy; Hayhurst, Lorna; Masters, John J.; Penariol, Roberta; Walter, Magnus W.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4432 - 4437