4-(1,1-二甲基乙基)-2-噻唑羧酸 1,1-二甲基乙酯合成路线 （共 4 条）
反应条件
1: oxalyl chloride / benzene / 0.25 h / Heating
2: 0.72 g / LiOBu-t / tetrahydrofuran / 1 h / Heating
View Scheme
参考文献
Kaye, Perry T.; Meakins, G. Denis; Willbe, Charles; Williams, Peter R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2335 - 2339
反应条件
1: 2.1 g / KOH, water / 0.08 h / Heating
2: oxalyl chloride / benzene / 0.25 h / Heating
3: 0.72 g / LiOBu-t / tetrahydrofuran / 1 h / Heating
View Scheme
参考文献
Kaye, Perry T.; Meakins, G. Denis; Willbe, Charles; Williams, Peter R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2335 - 2339
反应条件
1: 13.6 g / ethanol / 0.5 h / Heating
2: 2.1 g / KOH, water / 0.08 h / Heating
3: oxalyl chloride / benzene / 0.25 h / Heating
4: 0.72 g / LiOBu-t / tetrahydrofuran / 1 h / Heating
View Scheme
参考文献
Kaye, Perry T.; Meakins, G. Denis; Willbe, Charles; Williams, Peter R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2335 - 2339
反应条件
lithium tert-butylate in tetrahydrofuran
1 h; Heating;
参考文献
Kaye, Perry T.; Meakins, G. Denis; Willbe, Charles; Williams, Peter R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2335 - 2339
