5-溴-4-甲基噻唑-2-羧酸甲酯合成路线 （共 2 条）
反应条件
in methanol; dichloromethane
参考文献
Boehringer Ingelheim (Canada) Ltd.
Patent: US2003/236251 A1, 2003 ;
Location in patent: Page 28 ;
反应条件
n-butyllithium
1.) hexane, -60 deg C, 1 h, 2.) ether, 3.) ether, 5 min; Yield given. Multistep reaction;
参考文献
Kaye, Perry T.; Meakins, G. Denis; Willbe, Charles; Williams, Peter R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2335 - 2339
