1: With hydrogen; palladium 10 on activated carbon in methanol; phosphorus pentoxide P=22502.3 Torr; 72 h; 2: With hydrogenchloride in diethyl ether

1: With lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 12 h; Heating / reflux; 2: With sodium hydroxide in tetrahydrofuran; water T=0°C; 0.5 h; 3: With hydrogenchloride in diethyl ether T=0°C; 1 h;

hydrogenchloride in diethyl ether T=20°C; 2 h;

1.1: 1.5 h / Reflux 2.1: lithium aluminium tetrahydride / tetrahydrofuran / 10 - 20 °C / Cooling with isopropanol-dry ice 2.2: 10 - 20 °C 3.1: hydrogen / palladium 10 on activated carbon / methanol; phosphorus pentoxide / 72 h / 22502.3 Torr View Scheme

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 10 - 20 °C / Cooling with isopropanol-dry ice 1.2: 10 - 20 °C 2.1: hydrogen / palladium 10 on activated carbon / methanol; phosphorus pentoxide / 72 h / 22502.3 Torr View Scheme