4-(溴甲基)-2,6-二甲基吡啶合成路线 （共 2 条）
反应条件
hydrogen bromide
4 h; Heating;
参考文献
Mobinikhaledi; Foroughifar
Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 2 p. 405 - 412
反应条件
1: 4-hydroxy-1-methylsulfonylpiperidine With sodium hydride in DMF (N,N-dimethyl-formamide)
T=20°C; 0.333333 h;
2: 4-(bromomethyl)-2,6-dimethylpyridine in tetrahydrofuran; DMF (N,N-dimethyl-formamide)
T=20°C; 120 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/6925 A1, 2004 ;
Location in patent: Page/Page column 79 ;
WO 2004/006925 A1
