4-(苄氧基)-2-溴-1-甲氧基苯合成路线 （共 4 条）
反应条件
potassium hydroxide in water
2 h; Heating;
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
反应条件
1: 83 percent / bromine / CHCl3 / 1 h
2: 61 percent / potassium hydroxide / H2O / 2 h / Heating
View Scheme
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
反应条件
1: 1.) lithium di-isopropylamide, 2.) air / 1.) THF, -70 - -60 deg C, 2.) THF, 20 deg C, 22 h
2: 98 percent / conc. hydrochloric acid / tetrahydrofuran / 15 h / Ambient temperature
View Scheme
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
反应条件
air; lithium diisopropyl amide
1.) THF, -70 - -60 deg C, 2.) THF, 20 deg C, 22 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Dodsworth, David J.; Calcagno, Maria-Pia; Ehrmann, E. Ursula; Devadas, Bhatt; Sammes, Peter G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 2120 - 2124
