(5-碘-2-甲氧基苯基)甲胺合成路线 （共 2 条）
反应条件
ammonium acetate; sodium cyanoborohydride in methanol
T=20°C; 48 h;
参考文献
GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Patent: WO2006/31505 A1, 2006 ;
Location in patent: Page/Page column 28 ;
WO 2006/031505 A1
反应条件
1: 98 percent / K2CO3 / dimethylformamide / 20 °C
2: 40 percent / ammonium acetate; NaCNBH3 / methanol / 48 h / 20 °C
View Scheme
参考文献
Tchilibon, Susanna; Joshi, Bhalchandra V.; Kim, Soo-Kyung; Duong, Heng T.; Gao, Zhan-Guo; Jacobson, Kenneth A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 6 p. 1745 - 1758
