sodium carbonate; triphenylphosphine in methanol; toluene T=80°C; Suzuki Coupling; 24 h; Inert atmosphere;

1.1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 80 °C / |Inert atmosphere 1.2: pH 1 / |Inert atmosphere; |Cooling with ice 2.1: toluene-4-sulfonic acid / toluene / 12 h / |Reflux 3.1: sodium carbonate; triphenylphosphine / toluene; methanol / 24 h / 80 °C / |Inert atmosphere View Scheme

1: toluene-4-sulfonic acid / toluene / 12 h / |Reflux 2: sodium carbonate; triphenylphosphine / toluene; methanol / 24 h / 80 °C / |Inert atmosphere View Scheme