2-氟-4,5-二甲氧基苯甲酸合成路线 (共 4 条)
反应条件
potassium permanganate in water
1 h; Heating;
参考文献
Nie, Jun-ying; Kirk, Kenneth L.
Journal of Fluorine Chemistry, 1995 , vol. 74, # 2 p. 297 - 302
反应条件
1: 84.5 percent / AlCl3 / 1,2-dichloro-ethane / 2.5 h / -20 - 20 °C
2: 89 percent / Br2 / CHCl3 / 2 h / Ambient temperature
3: 1.) diethylamine, 2.) conc. HCl / 1.) i-Pr-OH, RT, 6 h, 2.) i-PrOH
View Scheme
参考文献
Stegmann, Hartmut B.; Deuschle, Gabriele; Schuler, Paul
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994 , # 3 p. 547 - 556
反应条件
1: 89 percent / Br2 / CHCl3 / 2 h / Ambient temperature
2: 1.) diethylamine, 2.) conc. HCl / 1.) i-Pr-OH, RT, 6 h, 2.) i-PrOH
View Scheme
参考文献
Stegmann, Hartmut B.; Deuschle, Gabriele; Schuler, Paul
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994 , # 3 p. 547 - 556
反应条件
hydrogenchloride; diethylamine
1.) i-Pr-OH, RT, 6 h, 2.) i-PrOH; Yield given. Multistep reaction;
参考文献
Stegmann, Hartmut B.; Deuschle, Gabriele; Schuler, Paul
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1994 , # 3 p. 547 - 556