20-羟基二十碳-5Z,8Z,11Z,14Z-四烯酸合成路线 （共 34 条）
反应条件
lithium hydroxide; toluene-4-sulfonic acid 1.) methanol, 23 deg C, 1.5 h; 2.) methanol, THF, 23 deg C, 1.5 h; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 24, # 1 p. 37 - 40
反应条件
1: hexamethylphosphoric acid triamide / 1.) -78 deg C, 30 min; 2.) from -78 deg C to 0 deg C, 90 min 2: saponification View Scheme
参考文献
Tetrahedron Letters, , vol. 24, # 1 p. 33 - 36
反应条件
1: 1.) n-butyllithium, 2.) hexamethylphosphorictriamide / 1.) THF, -78 deg C, 30 min; 2.) THF, -78 deg C, 1 h then at -78 deg C to -20 deg C, 1.5 h 2: 1.) 0.1 percent tosic acid; 2.) aq. lithium hydroxide / 1.) methanol, 23 deg C, 1.5 h; 2.) methanol, THF, 23 deg C, 1.5 h View Scheme
参考文献
Tetrahedron Letters, , vol. 24, # 1 p. 37 - 40
反应条件
human cytochrome P450 4F11 pH=7.4; aq. phosphate bufferEnzymatic reaction; Kinetics;
参考文献
Archives of Biochemistry and Biophysics, , vol. 494, # 1 p. 86 - 93
