1-甲基-1H-吡唑-4-羰酰氯合成路线 （共 3 条）
反应条件
thionyl chloride Heating;
参考文献
Agricultural and Biological Chemistry, , vol. 48, # 1 p. 45 - 50
反应条件
1: diethyl ether; ethanol / 20 °C 2: hydrogenchloride / water / |Reflux View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 49, # 6 p. 1422 - 1424
反应条件
1: 1-methyl-1H-pyrazole-4-carbonyl chloride With diazomethyl-trimethyl-silane in hexane; acetonitrile
T=0°C; 1 h;
2: hydrogen bromide With acetic acid in hexane; acetonitrile
T=20°C; 1.33333 h;
参考文献
ONO PHARMACEUTICAL CO., LTD.; COURTNEY, Steve; YARNOLD, Chris; FLANAGAN, Stuart; BRACE, Gareth; BARKER, John; ICHIHARA, Osamu; GADOULEAU, Elise; RICHARDSON, Anthony; KONDO, Takashi; IMAGAWA, Akira; NAKATANI, Shingo; SUZUKI, Ryo; KOUYAMA, Sho
Patent: WO2013/93484 A1, 2013 ;
Location in patent: Page/Page column 230; 231 ;
