6,7,8-三氟-1,4-二氢-4-氧代-3-喹啉羧酸乙酯合成路线 （共 15 条）
反应条件
1: 1.) K2CO3 / 1.) DMF 2: HCl / acetic acid / Heating View Scheme
参考文献
Dichiarante, Valentina; Pretali, Luca; Fasani, Elisa; Albini, Angelo
Journal of Photochemistry and Photobiology A: Chemistry, 2013 , vol. 265, p. 41 - 48
反应条件
potassium carbonate in N,N-dimethyl-formamide T=95°C; 10 h;
参考文献
Sunduru, Naresh; Gupta, Leena; Chauhan, Kuldeep; Mishra, Nripendra N.; Shukla, Praveen K.; Chauhan, Prem M.S.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1232 - 1244
反应条件
potassium carbonate T=190°C; 1.5 h; Yield given;
参考文献
Podanyi, Benjamin; Kereszturi, Geza; Vasvari-Debreczy, Lelle; Chinoin, Istvan Hermecz; Toth, Gabor
Magnetic Resonance in Chemistry, 1996 , vol. 34, # 11 p. 972 - 978
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 10 h / 95 °C
2: hydrogenchloride; water / acetic acid / 2 h / Reflux
3: acetonitrile / 7 h / 90 °C
View Scheme
参考文献
Sunduru, Naresh; Gupta, Leena; Chauhan, Kuldeep; Mishra, Nripendra N.; Shukla, Praveen K.; Chauhan, Prem M.S.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1232 - 1244
反应条件
sodium iodide in methanol; ice-water; N,N-dimethyl-formamide
参考文献
KYORIN SEIYAKU KABUSHIKI KAISHA
Patent: EP195135 B1, 1992 ;
