1: 3-chloro-pyridine With n-butyllithium in hexane T=-60°C; 1 h; 2: chloro-trimethyl-silane in tetrahydrofuran T=-60 - 20°C;

N,N,N',N,-tetramethylethylenediamine in diethyl ether T=-60°C; Product distribution; Further Variations:Reaction partnersReagentsSolventsTemperatures;

n-butyllithium 1.) THF. -60 deg C, 2.) THF, 1 h; var. lithium compounds, temp.; Product distribution;

copper(l) iodide; tetrabutyl ammonium fluoride; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; N,N-dimethyl-formamide T=20°C; Hiyama cross-coupling; 12 h;