5-溴-1-甲基-3-苯基苯并咪唑-2-酮合成路线 (共 4 条)
反应条件
potassium hydroxide in dimethyl sulfoxide
T=40°C; 24 h; Inert atmosphere;
参考文献
Beyer, Astrid; Reucher, Christine M. M.; Bolm, Carsten
Organic Letters, 2011 , vol. 13, # 11 p. 2876 - 2879
反应条件
potassium carbonate in methanol
T=50 - 55°C; 12 h;
参考文献
Bianchi; Butti; Rossi; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 321 - 326
反应条件
1: 87 percent / CHCl3 / 8 h / Heating
2: 42 percent / EtONa / ethanol / 3 h / Heating
3: 96 percent / K2CO3 / methanol / 12 h / 50 - 55 °C
View Scheme
参考文献
Bianchi; Butti; Rossi; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 321 - 326
反应条件
1: 42 percent / EtONa / ethanol / 3 h / Heating
2: 96 percent / K2CO3 / methanol / 12 h / 50 - 55 °C
View Scheme
参考文献
Bianchi; Butti; Rossi; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 4 p. 321 - 326