4-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯合成路线

参考文献

GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Karl H.; DRAGOVICH, Peter; GOSSELIN, Francis; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; ZAK, Mark; ZHANG, Yamin; ZHAO, Guiling; ZHENG, Xiaozhang; YUEN, Po-Wai
Patent: WO2013/127266 A1, 2013 ;
Location in patent: Page/Page column 153; 166 ;

188527-03-9N-BOC 4-(4-溴苯基硫代)哌啶

797750-44-84-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯

参考文献

Dragovich, Peter S.; Bair, Kenneth W.; Baumeister, Timm; Ho, Yen-Ching; Liederer, Bianca M.; Liu, Xiongcai; Liu, Yongbo; O'Brien, Thomas; Oeh, Jason; Sampath, Deepak; Skelton, Nicholas; Wang, Leslie; Wang, Weiru; Wu, Hongxing; Xiao, Yang; Yuen, Po-Wai; Zak, Mark; Zhang, Lei; Zheng, Xiaozhang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 17 p. 4875 - 4885

109384-19-2N-Boc-4-羟基哌啶

797750-44-84-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯

参考文献

Dragovich, Peter S.; Bair, Kenneth W.; Baumeister, Timm; Ho, Yen-Ching; Liederer, Bianca M.; Liu, Xiongcai; Liu, Yongbo; O'Brien, Thomas; Oeh, Jason; Sampath, Deepak; Skelton, Nicholas; Wang, Leslie; Wang, Weiru; Wu, Hongxing; Xiao, Yang; Yuen, Po-Wai; Zak, Mark; Zhang, Lei; Zheng, Xiaozhang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 17 p. 4875 - 4885

106-53-64-溴苯硫酚

797750-44-84-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯

参考文献

Dragovich, Peter S.; Bair, Kenneth W.; Baumeister, Timm; Ho, Yen-Ching; Liederer, Bianca M.; Liu, Xiongcai; Liu, Yongbo; O'Brien, Thomas; Oeh, Jason; Sampath, Deepak; Skelton, Nicholas; Wang, Leslie; Wang, Weiru; Wu, Hongxing; Xiao, Yang; Yuen, Po-Wai; Zak, Mark; Zhang, Lei; Zheng, Xiaozhang
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 17 p. 4875 - 4885

5382-16-14-羟基哌啶

797750-44-84-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯

参考文献

GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Karl H.; DRAGOVICH, Peter; GOSSELIN, Francis; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; ZAK, Mark; ZHANG, Yamin; ZHAO, Guiling; ZHENG, Xiaozhang; YUEN, Po-Wai
Patent: WO2013/127266 A1, 2013 ;

24424-99-5二碳酸二叔丁酯

797750-44-84-(4-氰基苯磺酰基)-哌啶-1-羧酸叔丁酯

参考文献

GENENTECH, INC.; FORMA TM, LLC; BAIR, Kenneth W.; BAUMEISTER, Timm R.; BUCKMELTER, Alexandre J.; CLODFELTER, Karl H.; DRAGOVICH, Peter; GOSSELIN, Francis; GUNZNER-TOSTE, Janet; HAN, Bingsong; LIN, Jian; LIU, Xiongcai; REYNOLDS, Dominic J.; SMITH, Chase C.; WANG, Zhongguo; ZAK, Mark; ZHANG, Yamin; ZHAO, Guiling; ZHENG, Xiaozhang; YUEN, Po-Wai
Patent: WO2013/127266 A1, 2013 ;