丁氧羰基-叔5-溴尿嘧啶-丙氨酸羟基合成路线 （共 8 条）
反应条件
1: 98 percent / H2 / palladium black / acetic acid / 11.5 h 2: 50 percent / H2O2 / aq. KOH / 2 h 3: 100 percent / Br2/aq. NaOH / 2 h / 30 - 40 °C 4: Ac2O / 2 h / 0 - 5 °C 5: NaHCO3 / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
反应条件
1: 81 percent / H2 / Pd/BaSO4 / toluene / 5 h / 120 °C 2: NH3 / H2O; toluene / 3 h / 50 °C 3: Aq. HCl / 2 h / 100 °C 4: Ac2O / 2 h / 0 - 5 °C 5: NaHCO3 / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
反应条件
1: NH3 / H2O; toluene / 3 h / 50 °C 2: Aq. HCl / 2 h / 100 °C 3: Ac2O / 2 h / 0 - 5 °C 4: NaHCO3 / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
反应条件
1: 50 percent / H2O2 / aq. KOH / 2 h 2: 100 percent / Br2/aq. NaOH / 2 h / 30 - 40 °C 3: Ac2O / 2 h / 0 - 5 °C 4: NaHCO3 / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
反应条件
1: Ac2O / 2 h / 0 - 5 °C 2: NaHCO3 / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
反应条件
1: Aq. HCl / 2 h / 100 °C 2: Ac2O / 2 h / 0 - 5 °C 3: NaHCO3 / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
反应条件
1: 100 percent / Br2/aq. NaOH / 2 h / 30 - 40 °C 2: Ac2O / 2 h / 0 - 5 °C 3: NaHCO3 / H2O; dioxane / 2 h / Ambient temperature View Scheme
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water 2 h; Ambient temperature; Yield given;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 52, # 2 p. 514 - 521
