(2R,5R)-5-羟基-1,2-哌啶二甲酸 2-甲酯 1-苄酯合成路线 （共 4 条）
反应条件
1: 94 percent / NaHCO3
2: 82 percent / TsOH / benzene / Heating
3: 93 percent / NaOMe
4: Et3N / tetrahydrofuran
5: diethyl ether
6: 52 percent / [Rh(OAc)2]2 / benzene / Heating
7: 93 percent / NaBH4 / methanol
View Scheme
参考文献
Shirude, Pravin S.; Kumar, Vaijayanti A.; Ganesh, Krishna N.
Tetrahedron, 2004 , vol. 60, # 42 p. 9485 - 9491
反应条件
1: 82 percent / TsOH / benzene / Heating
2: 93 percent / NaOMe
3: Et3N / tetrahydrofuran
4: diethyl ether
5: 52 percent / [Rh(OAc)2]2 / benzene / Heating
6: 93 percent / NaBH4 / methanol
View Scheme
参考文献
Shirude, Pravin S.; Kumar, Vaijayanti A.; Ganesh, Krishna N.
Tetrahedron, 2004 , vol. 60, # 42 p. 9485 - 9491
反应条件
1: 93 percent / NaOMe
2: Et3N / tetrahydrofuran
3: diethyl ether
4: 52 percent / [Rh(OAc)2]2 / benzene / Heating
5: 93 percent / NaBH4 / methanol
View Scheme
参考文献
Shirude, Pravin S.; Kumar, Vaijayanti A.; Ganesh, Krishna N.
Tetrahedron, 2004 , vol. 60, # 42 p. 9485 - 9491
反应条件
1: Et3N / tetrahydrofuran
2: diethyl ether
3: 52 percent / [Rh(OAc)2]2 / benzene / Heating
4: 93 percent / NaBH4 / methanol
View Scheme
参考文献
Shirude, Pravin S.; Kumar, Vaijayanti A.; Ganesh, Krishna N.
Tetrahedron, 2004 , vol. 60, # 42 p. 9485 - 9491
