反应条件
1: triethylamine, methane sulfonylchloride / CH2Cl2 / 1.) 0 deg C, 5 min, 2.) -20 deg C, 2 d 2: 1.) rose bengal, bis(triethyl ammonium) salt, oxygen, 2.) lithium tris-tert-butoxyaluminohydride / 1.) CCl4, methanol, 20 min, irrad., 2.) THF, -78 deg C, 20 min 3: 1.) BH3*DMS, 2.) 6 M HCl / 1a.) THF, RT, 20 min, 1b.) reflux, 30 min, 2.) reflux, 30 min 4: 82 percent / H2, conc. aq. HCl / 10percent Pd/C / methanol / 6 h / 2585.7 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 112, # 22 p. 8100 - 8112
