(S)-3-(boc-氨基)-2-氧代-1-氮杂卓乙酸合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; Hydrogenolysis;
参考文献
Amblard, Muriel; Daffix, Isabelle; Berge, Gilbert; Calmes, Monique; Dodey, Pierre; Pruneau, Didier; Paquet, Jean-Luc; Luccarini, Jean-Michel; Belichard, Pierre; Martinez, Jean
Journal of Medicinal Chemistry, 1999 , vol. 42, # 20 p. 4193 - 4201
反应条件
1.1: 85 percent / (benzotriazolyloxy)tris(Me2NH)phosphonium PF6(-); NaHCO3 / dimethylformamide / 12 h / 20 °C 2.1: NaH / tetrahydrofuran / 0.25 h / 20 °C 2.2: 95 percent / tetrahydrofuran / 5 h / 20 °C 3.1: 96 percent / H2 / 10 percent Pd/C / ethanol / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 20 p. 4193 - 4201
反应条件
1.1: NaH / tetrahydrofuran / 0.25 h / 20 °C 1.2: 95 percent / tetrahydrofuran / 5 h / 20 °C 2.1: 96 percent / H2 / 10 percent Pd/C / ethanol / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 42, # 20 p. 4193 - 4201
反应条件
1: H2 / 10percent Pd/C / methanol / 3 h 2: 25 percent / triethylamine / acetonitrile / 72 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 47, # 1 p. 104 - 109
反应条件
triethylamine in acetonitrile 72 h; Heating;
参考文献
Freidinger, Roger M.; Perlow, Debra Schwenk; Veber, Daniel F.
Journal of Organic Chemistry, 1982 , vol. 47, # 1 p. 104 - 109
