3-氨基-N-羟基-2-氧代苯并吡喃-6-胺氧化物合成路线 （共 4 条）
反应条件
in sulfuric acid; acetic acid
参考文献
Warner-Lambert Company
Patent: US4287126 A1, 1981 ;
反应条件
hydrogenchloride in chloroform
参考文献
Bonsignore, Leonardo; Loy, Giuseppe
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 1 p. 117 - 119
反应条件
1.1: 69 percent / sodium acetate / acetic anhydride / 3.5 h / 110 - 120 °C
2.1: 4-(dimethylamino)pyridine / tetrahydrofuran / 0.33 h / 20 °C
2.2: 93 percent / hydrazine hydrate / methanol; tetrahydrofuran / 0.33 h / 20 °C
3.1: 89 percent / TFA / CHCl3 / 3 h / 20 °C
View Scheme
参考文献
Kudale, Amit A.; Kendall, Jamie; Warford, C. Chad; Wilkins, Natasha D.; Bodwell, Graham J.
Tetrahedron Letters, 2007 , vol. 48, # 29 p. 5077 - 5080
反应条件
1: 80 percent / Et3N, DPPA / 24 h / Heating
2: 100 percent / HCl (gas) / CHCl3
View Scheme
参考文献
Bonsignore, Leonardo; Loy, Giuseppe
Journal of Heterocyclic Chemistry, 1998 , vol. 35, # 1 p. 117 - 119
