2-(4-氰基苯氧基)-2-甲基丙酸合成路线 （共 7 条）
反应条件
1: 88 percent / 3percent H2O2, KOH / H2O 2: 90 percent / Br2, NaOH / H2O / 0.5 h / 75 °C View Scheme
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
反应条件
1: 88 percent / 3percent H2O2, KOH / H2O 2: 90 percent / Br2, NaOH / H2O / 0.5 h / 75 °C 3: 90 percent / 2 N NaOH / tetrahydrofuran View Scheme
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
反应条件
1: 88 percent / 3percent H2O2, KOH / H2O 2: 90 percent / Br2, NaOH / H2O / 0.5 h / 75 °C 3: 80 percent / 2 N NaOH / tetrahydrofuran View Scheme
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
反应条件
potassium hydroxide; dihydrogen peroxide in water
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
反应条件
1: With methanol; lithium hydroxide; water in tetrahydrofuran
T=20°C;
2: With hydrogenchloride in tetrahydrofuran; water
pH=2;
参考文献
Yao, Wenqing; Xu, Meizhong; Zhang, Colin; Agrios, Konstantinos; Metcalf, Brian W.; Zhuo, Jincong
Patent: US2006/9471 A1, 2006 ;
Location in patent: Page/Page column 29 ;
反应条件
sodium hydroxide in water; acetone
参考文献
Montefiore Medical Center
Patent: US4921997 A1, 1990 ;
反应条件
sodium hydroxide
4 h; Heating;
参考文献
Lalezari, Iraj; Lalezari, Parviz
Journal of Medicinal Chemistry, 1989 , vol. 32, # 10 p. 2352 - 2357
