(3-氨基-5-氯苯基)甲醇合成路线 （共 6 条）
反应条件
hydrogenchloride; iron in ethanol
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 9 p. 1111 - 1118
反应条件
1: 62 percent / (NH4)2S / methanol / 5 h / Heating 2: 1.) HNO2, 2.) CuCl2, CuCl, 12percent aq. HCl / 1.) 0 deg C, 2.) 60 deg C, 1 h 3: 81 percent / Fe, HCl (gas) / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 9 p. 1111 - 1118
反应条件
1: 1.) HNO2, 2.) CuCl2, CuCl, 12percent aq. HCl / 1.) 0 deg C, 2.) 60 deg C, 1 h 2: 81 percent / Fe, HCl (gas) / ethanol View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 9 p. 1111 - 1118
反应条件
1: 65 percent / aq. HBF4, NaNO2 / -5 °C 2: 25 percent / Heating 3: 73 percent / MnO2 / benzene / 24 h / Heating View Scheme
参考文献
Meindl; Von Angerer; Schonenberger; Ruckdeschel
Journal of Medicinal Chemistry, 1984 , vol. 27, # 9 p. 1111 - 1118
反应条件
1: 65 percent / aq. HBF4, NaNO2 / -5 °C 2: 25 percent / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 27, # 9 p. 1111 - 1118
反应条件
1: 65 percent / aq. HBF4, NaNO2 / -5 °C
2: 25 percent / Heating
3: 73 percent / MnO2 / benzene / 24 h / Heating
4: 1 h / 80 °C
5: LiAlH4 / diethyl ether / 2 h / Heating
View Scheme
参考文献
Meindl; Von Angerer; Schonenberger; Ruckdeschel
Journal of Medicinal Chemistry, 1984 , vol. 27, # 9 p. 1111 - 1118
