反应条件
1: 97 percent / diphenylphosphoryl azide, Et3N / dimethylformamide / 1.) 0 deg C, 5 h, 2.) RT, 16 h
2: H2 / 5percent Pd/C / dioxane; methanol / 18 h / 760 Torr / Ambient temperature
3: 67 percent / N,N-dimethyl-acetamide / 144 h / 25 °C
View Scheme
参考文献
Piper, James R.; McCaleb, George S.; Montgomery, John A.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 2 p. 291 - 294
