4-(羟基甲基)萘-1-甲腈合成路线 （共 12 条）
反应条件
1: pyridine / benzene / 6 h 2: 5 percent Chromat. / methanol / Irradiation View Scheme
参考文献
DeCosta, D. P.; Pincock, J. A.
Canadian Journal of Chemistry, 1992 , vol. 70, # 7 p. 1879 - 1885
反应条件
potassium hydroxide in ethanol
3 h;
参考文献
Fasani, E.; d'Alessandro, N.; Albini, A.; Mariano, P. S.
Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 829 - 835
反应条件
sodium tetrahydroborate in ethanol
参考文献
DeCosta, Dayal P.; Pincock, James A.
Journal of the American Chemical Society, 1993 , vol. 115, # 6 p. 2180 - 2190
反应条件
1: 46 percent / N-methylpyrrolidinone / Heating
2: N-bromosuccinimide / CCl4 / 4 h / Heating; Irradiation
3: acetic acid / 5 h / Heating
4: 49 percent / KOH / aq. ethanol / 3 h / Heating
View Scheme
参考文献
McCullough, John J.; MacInnis, W. Keith; Lock, Colin J. L.; Faggiani, Rommulo
Journal of the American Chemical Society, 1982 , vol. 104, # 17 p. 4644 - 4658
反应条件
1: N-bromosuccinimide / CCl4 / 4 h / Heating; Irradiation
2: acetic acid / 5 h / Heating
3: 49 percent / KOH / aq. ethanol / 3 h / Heating
View Scheme
参考文献
McCullough, John J.; MacInnis, W. Keith; Lock, Colin J. L.; Faggiani, Rommulo
Journal of the American Chemical Society, 1982 , vol. 104, # 17 p. 4644 - 4658
反应条件
potassium hydroxide in methanol; acetonitrile
5 h; Irradiation;
参考文献
Fasani, E.; d'Alessandro, N.; Albini, A.; Mariano, P. S.
Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 829 - 835
反应条件
potassium hydroxide in methanol; acetonitrile
3 h; Irradiation;
参考文献
Fasani, E.; d'Alessandro, N.; Albini, A.; Mariano, P. S.
Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 829 - 835
反应条件
potassium hydroxide; toluene in acetonitrile
3 h; Irradiation;
参考文献
Fasani, E.; d'Alessandro, N.; Albini, A.; Mariano, P. S.
Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 829 - 835
反应条件
1: 87 percent / AlCl3 / CH2Cl2 / 1.) 0 deg C; 2.) ambient temp. 4 h; 3.) reflux, 2.5 h
2: 94 percent / NaOCl / H2O / 4.5 h / Heating
3: 25 percent / LiAlH4 / diethyl ether / 1.) reflux, 3 h; 2.) room temperature, 14 h
4: 64 percent
View Scheme
参考文献
Dixon, Elisabeth A.; Fischer, Alfred; Robinson, Frank P.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 2629 - 2641
反应条件
1: 25 percent / LiAlH4 / diethyl ether / 1.) reflux, 3 h; 2.) room temperature, 14 h
2: 64 percent
View Scheme
参考文献
Dixon, Elisabeth A.; Fischer, Alfred; Robinson, Frank P.
Canadian Journal of Chemistry, 1981 , vol. 59, p. 2629 - 2641
