N-甲基-N-亚硝基对甲苯磺酰胺合成路线 （共 111 条）
反应条件
potassium hydroxide in methanol; water T=20°C; 1.16667 h;
参考文献
Pinho, Vagner D.; Gutmann, Bernhard; Miranda, Leandro S. M.; De Souza, Rodrigo O. M. A.; Kappe, C. Oliver
Journal of Organic Chemistry, 2014 , vol. 79, # 4 p. 1555 - 1562
反应条件
potassium hydroxide in methanol; water T=20°C; 1.16667 h;
参考文献
Pinho, Vagner D.; Gutmann, Bernhard; Miranda, Leandro S. M.; De Souza, Rodrigo O. M. A.; Kappe, C. Oliver
Journal of Organic Chemistry, 2014 , vol. 79, # 4 p. 1555 - 1562
反应条件
potassium hydroxide in water T=20°C; 1.16667 h; Concentration;
参考文献
Pinho, Vagner D.; Gutmann, Bernhard; Miranda, Leandro S. M.; De Souza, Rodrigo O. M. A.; Kappe, C. Oliver
Journal of Organic Chemistry, 2014 , vol. 79, # 4 p. 1555 - 1562
反应条件
potassium hydroxide in tetrahydrofuran; methanol; water T=20°C; Arndt-Eistert Homologation;
参考文献
Mastronardi, Federica; Gutmann, Bernhard; Oliver Kappe
Organic Letters, 2013 , vol. 15, # 21 p. 5590 - 5593
反应条件
potassium hydroxide in tetrahydrofuran; methanol; water T=-10°C; Arndt-Eistert Homologation;
参考文献
Mastronardi, Federica; Gutmann, Bernhard; Oliver Kappe
Organic Letters, 2013 , vol. 15, # 21 p. 5590 - 5593
反应条件
potassium hydroxide in tetrahydrofuran; methanol; water T=20°C; Overall yield = 97 percent; Overall yield = 232 mg;
参考文献
Mastronardi, Federica; Gutmann, Bernhard; Oliver Kappe
Organic Letters, 2013 , vol. 15, # 21 p. 5590 - 5593
反应条件
1: N-methyl-N-nitroso-p-toluene-sulphonamide With potassium hydroxide in diethyl ether; water 2: 2-amino-6-methyl-benzoic acid in diethyl ether 1 h;
参考文献
Schuler, Elisabeth; Juanico, Nacho; Teixido, Jordi; Michelotti, Enrique L.; Borrell, Jose I.
Heterocycles, 2006 , vol. 67, # 1 p. 161 - 173
反应条件
potassium hydroxide in tetrahydrofuran; methanol; water T=20°C;
参考文献
Mastronardi, Federica; Gutmann, Bernhard; Oliver Kappe
Organic Letters, 2013 , vol. 15, # 21 p. 5590 - 5593
反应条件
sodium hydroxide; sodium lauryl sulfate; β-cyclodextrin in water; acetonitrile T=25°C; also with tetradecyltrimethylammonium bromide; Rate constant;
参考文献
Astray; Garcia-Rio; Lodeiro; Mejuto; Moldes; Morales; Moyano
International Journal of Chemical Kinetics, 2010 , vol. 42, # 5 p. 316 - 322
反应条件
potassium hydroxide in diethyl ether; ethanol; water
参考文献
ELI LILLY AND COMPANY
Patent: WO2004/4706 A1, 2004 ;
Location in patent: Example 3 ;
