1,3-二甲基-2-咪唑啉酮合成路线 （共 79 条）
反应条件
1.1: dichloromethane / 2 h / 20 °C / |Inert atmosphere 2.1: citric acid / dichloromethane 2.2: 37 °C / pH 7.4 / |Inert atmosphere View Scheme
参考文献
Macromolecules, , vol. 46, # 13 p. 5157 - 5166
反应条件
1.1: pyridine; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 1.25 h / 20 °C / |Inert atmosphere 2.1: dichloromethane / 2 h / 20 °C / |Inert atmosphere 3.1: citric acid / dichloromethane 3.2: 37 °C / pH 7.4 / |Inert atmosphere View Scheme
参考文献
Macromolecules, , vol. 46, # 13 p. 5157 - 5166
反应条件
sodium hydride 1.) dioxane, from 55 deg C to 60 deg C, 4 h, 2.) dioxane, reflux, 3.5 h; Yield given. Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 24, # 9 p. 1089 - 1092
反应条件
T=37°C; 0.5 h; aq. phosphate bufferEnzymatic reaction;
参考文献
Organic Letters, , vol. 10, # 8 p. 1517 - 1520
反应条件
in nitromethane Ambient temperature; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 102, # 11 p. 3928 - 3939
反应条件
n-butyllithium Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 1 p. 228 - 236
反应条件
in toluene 10 h; Heating;
参考文献
Chemistry Letters, , # 8 p. 758 - 759
参考文献
Tanaka, Hidenori; Yoshimura, Yayoi; Juergensen, Malene R.; Cuesta-Seijo, Jose A.; Hindsgaul, Ole
Angewandte Chemie - International Edition, 2012 , vol. 51, # 46 p. 11531 - 11534
Angew. Chem., 2012 , vol. 124, # 46 p. 11699 - 11702,4
反应条件
in CD3NO2 Ambient temperature; Product distribution;
参考文献
Journal of the American Chemical Society, , vol. 102, # 11 p. 3928 - 3939
反应条件
in water-d2 T=37°C; 1 h;
参考文献
Angewandte Chemie - International Edition, , vol. 51, # 46 p. 11531 - 11534
Angew. Chem., , vol. 124, # 46 p. 11699 - 11702,4
