1,3-二甲基-2-咪唑啉酮合成路线 （共 79 条）
反应条件
potassium hydroxide; 18-crown-6 ether in diethylene glycol dimethyl ether; para-xylene; water
参考文献
Union Carbide Corporation
Patent: US4769505 A1, 1988 ;
反应条件
KPF6 Substitution; deoxygenation;
参考文献
Del Fresno, Montserrat; El-Faham, Ayman; Carpino, Louis A.; Royo, Miriam; Albericio, Fernando
Organic Letters, 2000 , vol. 2, # 23 p. 3539 - 3542
反应条件
sodium methylate in methanol
参考文献
Fujisawa Pharmaceutical Co., Ltd.
Patent: US5994368 A1, 1999 ;
参考文献
Ihara Chemical Industry Co., Ltd.
Patent: US6166246 A1, 2000 ;
反应条件
methanesulfonic acid in water; 1,1'-carbonyldiimidazole
反应条件
1: 1,3-dimethyl-imidazolidin-2-one With trichlorophosphate in toluene
T=65°C; 20 h; Inert atmosphere;
2: N-butylamine in dichloromethane; toluene
T=0 - 60°C; Inert atmosphere;
3: With sodium hydroxide in dichloromethane; toluene
T=0°C;
参考文献
Gao, Jian; He, Liang-Nian; Miao, Cheng-Xia; Chanfreau, Sebastien
Tetrahedron, 2010 , vol. 66, # 23 p. 4063 - 4067
反应条件
1: oxalyl dichloride / benzene / 5 h / 20 °C / Inert atmosphere
2: triethylamine / dichloromethane / 72 h / 20 °C
View Scheme
参考文献
Bell, Jason R.; Luo, Huimin; Dai, Sheng
Tetrahedron Letters, 2011 , vol. 52, # 29 p. 3723 - 3725
反应条件
ammonium chloride; lithium hexamethyldisilazane in tetrahydrofuran
参考文献
Daiso Co., Ltd.
Patent: US6268515 B1, 2001 ;
参考文献
Montforts, Franz-Peter; Gesing-Zibulak, Ingrid; Grammenos, Wassilios; Schneider, Manfred; Laumen, Kurt
Helvetica Chimica Acta, 1989 , vol. 72, p. 1852 - 1859
