4-(2-吡啶基)-3-丁炔-2-醇合成路线 （共 4 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in dimethyl sulfoxide; triethylamine
T=40 - 45°C; 11.5 h;
参考文献
Zhang, Xiaobing; Lu, Zhan; Fu, Chunling; Ma, Shengming
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 16 p. 3258 - 3263
反应条件
sodium tetrahydroborate in ethanol
T=0°C; 1 h;
参考文献
Schubert, Thomas; Hummel, Werner; Kula, Maria-Regina; Mueller, Michael
European Journal of Organic Chemistry, 2001 , # 22 p. 4181 - 4187
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine
T=20°C; Sonogashira reaction; Inert atmosphere;
参考文献
Chernyak, Dmitri; Gadamsetty, Surendra Babu; Gevorgyan, Vladimir
Organic Letters, 2008 , vol. 10, # 11 p. 2307 - 2310
反应条件
1.1: nBuLi / tetrahydrofuran; hexane / 0.25 h / 0 °C
1.2: 36 percent / tetrahydrofuran; hexane / 2.5 h / -78 - 20 °C
2.1: NaBH4 / ethanol / 1 h / 0 °C
View Scheme
参考文献
Schubert, Thomas; Hummel, Werner; Kula, Maria-Regina; Mueller, Michael
European Journal of Organic Chemistry, 2001 , # 22 p. 4181 - 4187
