(6-溴-2-吡啶)苯基-甲酮合成路线 （共 3 条）
反应条件
1: 2,6-Dibromopyridine With n-butyllithium in diethyl ether; hexane
T=-78°C; 1 h;
2: benzonitrile in diethyl ether; hexane
T=-78 - 20°C; 2 h;
3: With hydrogenchloride in diethyl ether; hexane
T=20°C; 0.333333 h;
参考文献
Ishikawa, Shunpei; Hamada, Tomoaki; Manabe, Kei; Kobayashi, Shu
Synthesis, 2005 , # 13 art. no. F02405SS, p. 2176 - 2182
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in toluene
3 h;
参考文献
Hermann, Christine K. F.; Sachdeva, Yesh P.; Wolfe, James F.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 1061 - 1065
反应条件
1: C5H3BrClMgN*ClLi With CuCN*2LiCl
T=-10°C; 0.25 h;
2: benzoyl chloride
参考文献
Ludwig-Maximilians-Universitaet Muenchen
Patent: EP1582523 A1, 2005 ;
Location in patent: Page/Page column 12 ;
