1: H2 / Ru2Cl4[(R)-(+)-p-tolyl-BINAP]2Et3N / methanol / 140 h / 20 °C / 37503 Torr 2: 0.24 g / 6 N HCl / 20 h / Heating View Scheme

1: H2 / Ru2Cl4[(R)-(+)-p-tolyl-BINAP]2Et3N / methanol / 140 h / 20 °C / 37503 Torr 2: 0.24 g / 6 N HCl / 20 h / Heating 3: 0.18 g / aq. NaOH / tetrahydrofuran / 40 h / 20 °C / pH 9 View Scheme

<b>Multi-step reaction with 2 steps<br /> </b>1: 84 percent / sodium acetate / acetic anhydride / 0.33 h / 100 &deg;C<br />2: 85 percent / 0.3 percent NaOH / 0.75 h / 100 &deg;C<br /> <br /> &nbsp;